Upper Level
Research on Male Infertility
Journal of Traditional Chinese Medicine
Page 728, Vol. 41 No. 12, December 2000
Clinical Observation on 120 Cases of Male infertility Treated with Herbal
Remedy
Li Jinkun, Shen Ming, Xu Xiaolin, et al
Authers' address: First Affiliated Hospital of Kunming Medical College, Kunming 650032
ABSTRACT FROM ORIGINAL ARTICLE
120 male infertility cases: average age 27-+2; 72 male health control group: average age 26-+2
with fertility ability
120 male infertility cases were treated by oral administration of herbal remedy decoction, one dose
daily for 2 consecutive months and 72 cases were used as control group. Sperm analysis was
made before and after treatment. America Hamilton-Thorne Research Equiment--CASA was used
to analyze sperm: VAP, VSL, VCL, ALH, BCF, VSL/VAP(ATR), LIN, ELO and AREA.
Results showed that after treatment the motility rate, rapid mobility rate and various mobility indices
of sperm were improved in the treatment group and among the 120 cases treated, 16 case's
spouses had pregnancy. It is proved that the herbal decoction has a definite therapeutic effect on
male infertility, and the therapeutic mechanism might be increase of mobility rate, rapid mobility rate
and improvement of mobility indices of sperm.
Key words: Infertility, Male/ TCM therapy, Herbal remedy
Table 1. Data on control group as well as fefore and after treatment in treatment group
Group Cases VAP VSL VCL ALH BCF STR LIN ELO AREA
Hz % % %
Control 72 58.0±10.3 48.2±8.9 81.5±15.7 2.8±1.4 13.9±10.1 82.9±5.5 61.2±8.1 69.3±7.4 3.7±0.9
Treatment
Before 120 35.6±11.7* 29.7±10.9* 58.6±24.9* 2.7±1.6 23.9±10.9* 72.7±19.9* 47.6±16.4* 58.0±16.6* 4.1±1.5*
After 120 49.1±13.4# 40.1±11.6# 76.1±21.6# 3.3±1.2# 23.4±8.7# 81.5±5.8# 55.6±9.7# 67.4±6.3# 3.4±0.8#
* means Treatment group before treatment compared with control group, there is significant difference (P<
0.05);
# means compared before treatment and after treatment in treatment group, there is very significant
difference ( P<0.01)
Table 2. Sperm density, mobility and rapid mobility in control group as well as before and after
treatment in treatment group
Group Cases Density Mobility Rapid mobility
x million/ml % %
Control 72 57.4±26.4 46.2±17.8 33.9±18.6
Treatment
Before 120 52.6±36.6* 24.9±14.1* 14.6±11.1*
After 120 59.7±27.0 43.9±19.9# 31.7±21.1#
* means Treatment group before treatment compared with control group, there is very significant difference
(P< 0.01);
# means compared before and after treatment in treatment group, there is very significant difference (
P<0.01)
Upper Level
Research on Male Infertility
Journal of Traditional Chinese Medicine
Page 728, Vol. 41 No. 12, December 2000
Clinical Observation on 120 Cases of Male infertility Treated with Herbal
Remedy
Li Jinkun, Shen Ming, Xu Xiaolin, et al
Authers' address: First Affiliated Hospital of Kunming Medical College, Kunming 650032
ABSTRACT FROM ORIGINAL ARTICLE
120 male infertility cases: average age 27-+2; 72 male health control group: average age 26-+2
with fertility ability
120 male infertility cases were treated by oral administration of herbal remedy decoction, one dose
daily for 2 consecutive months and 72 cases were used as control group. Sperm analysis was
made before and after treatment. America Hamilton-Thorne Research Equiment--CASA was used
to analyze sperm: VAP, VSL, VCL, ALH, BCF, VSL/VAP(ATR), LIN, ELO and AREA.
Results showed that after treatment the motility rate, rapid mobility rate and various mobility indices
of sperm were improved in the treatment group and among the 120 cases treated, 16 case's
spouses had pregnancy. It is proved that the herbal decoction has a definite therapeutic effect on
male infertility, and the therapeutic mechanism might be increase of mobility rate, rapid mobility rate
and improvement of mobility indices of sperm.
Key words: Infertility, Male/ TCM therapy, Herbal remedy
Table 1. Data on control group as well as fefore and after treatment in treatment group
Group Cases VAP VSL VCL ALH BCF STR LIN ELO AREA
Hz % % %
Control 72 58.0±10.3 48.2±8.9 81.5±15.7 2.8±1.4 13.9±10.1 82.9±5.5 61.2±8.1 69.3±7.4 3.7±0.9
Treatment
Before 120 35.6±11.7* 29.7±10.9* 58.6±24.9* 2.7±1.6 23.9±10.9* 72.7±19.9* 47.6±16.4* 58.0±16.6* 4.1±1.5*
After 120 49.1±13.4# 40.1±11.6# 76.1±21.6# 3.3±1.2# 23.4±8.7# 81.5±5.8# 55.6±9.7# 67.4±6.3# 3.4±0.8#
* means Treatment group before treatment compared with control group, there is significant difference (P<
0.05);
# means compared before treatment and after treatment in treatment group, there is very significant
difference ( P<0.01)
Table 2. Sperm density, mobility and rapid mobility in control group as well as before and after
treatment in treatment group
Group Cases Density Mobility Rapid mobility
x million/ml % %
Control 72 57.4±26.4 46.2±17.8 33.9±18.6
Treatment
Before 120 52.6±36.6* 24.9±14.1* 14.6±11.1*
After 120 59.7±27.0 43.9±19.9# 31.7±21.1#
* means Treatment group before treatment compared with control group, there is very significant difference
(P< 0.01);
# means compared before and after treatment in treatment group, there is very significant difference (
P<0.01)
Upper Level
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